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Symbol
Name
ID
Atf4
activating transcription factor 4
MGI:88096
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
decreased pancreatic beta cell proliferation
increased pancreatic beta cell proliferation
abnormal pancreatic acinus morphology
abnormal pancreatic acinar cell morphology
abnormal pancreatic acinar cell zymogen granule morphology
exocrine pancreas hypoplasia
endocrine/exocrine gland phenotype
increased pancreatic beta cell mass
abnormal pancreas morphology
decreased insulin secretion
increased insulin secretion
Availability Mouse Genotype
Atf4tm1Tow/Atf4tm1Tow
Tg(CMV-Atf4)1Kry/0 *
Tg(Col1a1-Atf4)1Kry/0
Atf4tm1Kry/Atf4tm1Kry
Tg(Col1a1-cre)1Kry/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory